The aim of this experimental study was to evaluate the use of eggshell membrane in the protection of brain tissue from the harmful mechanical effect of metallic microsurgical instruments during neurosurgical interventions. Methods: Thirty uncovered fresh cadaveric cow brains were equally divided into two groups: group with eggshell membrane group (Group I) and without eggshell membrane group (Group II). In Group I, eggshell membrane was sprawled over the left lateral side of the interhemispheric sulcus of the anterior brain surface. The mechanical traumatic effects of the metallic surgical instruments were divided into three groups: minor, moderate and severe. Results: In Group I (n=15), the number of minor injured brains was found to be 12 (80%). In Group II (n=15), the number of minor injured brains was found to be 5 (33.33%). On the contrary, the number of moderately injured brains parenchyma in Group I cow brains was estimated to be 2 (13.33%). However, the number of moderately injured brains in Group II was found to be 9 (60%). The number of severe injury was found to be 1 (6.67%) in Group II. The number of same injury was also found to be 1 (6.67%) in Group I. Conclusion: This study showed that protecting the naked brain tissue from the mechanical injury effect of metallic microsurgical instruments with covering of eggshell membrane is feasible. It is believed that this material might contribute to the practical microneurosurgery in protecting the brain tissue.
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